Hormones · The female-cycle estrogen
Men Women (soon)
Estradiol drives every phase of the menstrual cycle. Follicular-phase E2 reveals ovarian function; mid-cycle peak confirms imminent ovulation; post-menopausal levels mark the transition.
Optimal range
30–100 (cycle day 3)pg/mL
Avg. cost (US)
$65
Test frequency
Annually; with full cycle map every 3–5 years
When to measure
Cycle day 3 (baseline ovarian function) OR follow across cycle for a fuller picture. Postmenopausal: any day.
How to measure
Ultra-sensitive estradiol (LC-MS/MS) — standard immunoassays are unreliable at low postmenopausal values.
Average cost
≈ $65 cash price. Often covered by insurance with relevant ICD-10.
Test these together
These biomarkers contextualize and unlock a clearer picture than any single value can.
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