Cardiovascular · Apolipoprotein B
Men Women (soon)
ApoB(ApoB)
ApoB counts every atherogenic particle in your blood — LDL, IDL, VLDL, Lp(a). It is a better cardiovascular risk predictor than LDL-C, full stop.
Optimal range
Range varies by individual.
Avg. cost (US)
$55
Test frequency
Annually; quarterly during active intervention
When to measure
Fasted 12 hours for accurate triglycerides (ApoB itself does not require fasting, but the panel typically does).
How to measure
Direct immunoassay or LC-MS. NMR LipoProfile gives ApoB-particle count alongside particle size.
Average cost
≈ $55 cash price. Often covered by insurance with relevant ICD-10.
Signs your level is off
Symptoms if low
Rare.
Symptoms if high
CVD risk.
If your level is low
Plant sterols: GI
Supplement
Plant Sterols· 2 g/day
Form: Beta-sitosterol
Lowers ApoB-containing lipoproteins.
Foods
- Nuts
Lifestyle
- Low-carb diet
Caution: Plant sterols: GI
If your level is high
Berberine: interactions
Supplement
Berberine· 500 mg 3x/day
Form: Extract
Reduces ApoB production in liver.
Foods
- High-fat diet
Lifestyle
- Balanced diet
Medication (if prescribed)
Evolocumab· 140 mg/2 weeks
Form: Injectable
Reference only. Speak with a licensed clinician before any prescription intervention.
Caution: Berberine: interactions
Test these together
These biomarkers contextualize ApoB and unlock a clearer picture than any single value can.
Deeper reading
Protocols that move this marker
Selected studies
AMORIS PubMed
The prime report
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