Inflammation · Systemic load
Men Women (soon)
CRP (hs-CRP)(hsCRP)
High-sensitivity C-reactive protein measures the same protein as standard CRP but at a sensitivity that resolves chronic, low-grade systemic inflammation.
Optimal range
Range varies by individual.
Avg. cost (US)
$45
Test frequency
Annually; quarterly during inflammation-focused intervention
When to measure
When generally well — acute illness or recent intense exercise can spike values 10–100×. Avoid drawing within 7 days of a cold, hard workout, or injury.
How to measure
Standard immunoassay.
Average cost
≈ $45 cash price. Often covered by insurance with relevant ICD-10.
Signs your level is off
Symptoms if low
Rare; possible undernutrition or low immune activity.
Symptoms if high
Chronic inflammation; increased CVD risk, fatigue, joint pain.
If your level is low
Curcumin: GI upset >2g
Supplement
Curcumin· 500-1000 mg/day
Form: Turmeric extract with piperine
Inhibits NF-kB pathway to reduce cytokine production.
Foods
- Turmeric
- ginger
Lifestyle
- Intermittent fasting
Medication (if prescribed)
Aspirin (anti-inflammatory)· 81 mg/day
Form: Low-dose aspirin
Reference only. Speak with a licensed clinician before any prescription intervention.
Caution: Curcumin: GI upset >2g
If your level is high
Omega-3 >3g: bleeding risk
Supplement
Omega-3 (EPA/DHA)· 3-6 g/day
Form: Fish oil capsules
Reduces pro-inflammatory eicosanoids.
Foods
- Berries
- green tea
Lifestyle
- HIIT
- 7-9 h sleep
Medication (if prescribed)
Statins (e.g., atorvastatin)· 10-40 mg/day
Form: Oral tablet
Reference only. Speak with a licensed clinician before any prescription intervention.
Caution: Omega-3 >3g: bleeding risk
Test these together
These biomarkers contextualize CRP (hs-CRP) and unlock a clearer picture than any single value can.
Protocols that move this marker
Selected studies
JUPITER Trial NEJM; CANTOS NEJM
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